♥ What is the concentration of lithium in one 200mg tablet of ibuprofen?
Posted by admin in Google tablet Saturday, 27 February 2010 17:14 2 Comments
Is it only trace or substantial amounts, specifically?
Plasma half-life of either not a necessary detail at this point; I am just concerned with the concentration of lithium therein per pill (200mg) tablet. 500 or 800mg concentrations not needed.
Oh! Please don’t say “Google it” … i already did that. Thanks.
xoxo
♥
Well, i assume that it’s moreso an inactive ingredient i suppose but it does contain lithium. I was thinking it is in trace amounts only.
Caffeine is also present in ibuprofen/acetaminophen; but this too in trace amounts.
Ibuprofen can increase lithium levels in the blood leading to eventual lithium toxicity. That is why certain NSAIDs cannot be mixed with other scripts containing lithium.
But the concentration in a tablet of ibuprofin isn’t the same as an tablet of lithium carbonate. The levels are much different.
Thank you for answering though!
I know this ….. *thinks* maybe i was thinking of a different NSAID? I could’ve sworn Ibup contained trace amounts in addition to it’s effects of blocking/reducing excretion of lithium to the kidneys etc.
I am going to read up some more on this presently. Thank You for answering!
xoxo
*edit* Ken: Maybe? It’s possible *sighs* I’m tired LOL. If i’m wrong then I’m wrong.
Thank you also, for answering. xoxo
Ibuprofen does not contain any lithium. It’s molecular formula is C13H18O2. Lithium is a naturally occurring mineral so I suppose it is possible that specific batches are contaminated with very small amounts of lithium but I cannot think of any reason why that would be.
I think you may be confused because ibuprofen can increase the concentration of lithium in the blood. This is a warning for people who are taking prescription lithium and who may be considering taking over the counter ibuprofen. Lithium is a very effective and relatively safe medication, but the difference between the therapeutic dose and the toxic dose is very slim. People who are on lithium usually have to get regular blood tests to make sure that their blood lithium concentration is in this normal range; not too low to relieve symptoms and not high enough to cause liver damage.
Ibuprofen increases the concentration of lithium in the blood not by adding more lithium—it does not contain any—but through some other biochemical interaction. If you are taking lithium I would not recommend taking ibuprofen without first speaking to a health care professional such as a physician or pharmacist. If you are considering starting lithium therapy be sure to tell your prescriber about all of the medications that you are taking, including over the counter meds like ibuprofen, other prescription medications, herbal supplements and vitamins.
I have some knowledge of drugs like this and I have never heard of it being sold as a lithium salt. It contains no lithium itself, being merely carbon, hydrogen and oxygen.
Most likely, if sold as a salt it would be the one of the sodium, potassium, calcium or magnesium salts. It does increase blood levels of lithium if lithium is co-administered, this is a known drug interaction.
You may be thinking of ibuprofen lysine, in which the lysine increases the solubility of ibuprofen.